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The Base and Plus Configurations for Intel® Select Solutions for Genomics Analytics.

Ingredient

Intel® Select Solutions for Genomics Analytics Base Configuration
Intel Select Solutions for Genomics Analytics Plus Configuration

Application Nodes

1 x application node (also the compute node for the Base configuration)

1 x application node

Platform

1 x Intel® Server Board S2600WFT**

1 x Intel Server Board S2600WFT**

Processor

2 x Intel® Xeon® Gold 6152 processor (22 cores, 2.10 GHz), Intel® Xeon Gold 6252 processor (24 cores, 2.10 GHz), or a higher number Intel® Xeon® Scalable processor

2 x Intel Xeon Gold 6136 processor (12 cores, 3.0 GHz), Intel Xeon Gold 6226 processor (12 cores 2.70 GHz), or a higher number Intel Xeon Scalable processor

Memory

12 x 16 GB DDR4-2666MHz 1DC (total capacity 192 GB or higher)

12 x 16 GB DDR4-2666MHz 1DC (total capacity 192 GB or higher)

Host Adapters

 

1 x 100HFA016LS Intel® Omni-Path Host Fabric Interface (Intel® OP HFI) Adapter, PCIe* x16

Compute Nodes

 

4 x compute nodes

Platform

 

1 x Intel Server Board S2600WFT

Processor

 

2 x Intel® Xeon® Platinum 8180 processor (28 cores, 2.50 GHz), Intel® Xeon® Platinum 8280 processor (28 cores, 2.70 GHz), or a higher number Intel Xeon Scalable processor

Memory

 

12 x 16 GB DDR4-2666MHz 1DC (total capacity 192 GB or higher)

Local Storage

2 x 480 GB Intel® SSD DC S4510 (mirrored)

2 x 480 GB Intel SSD DC S4510 (mirrored)

Storage

4 x 4 TB Intel SSD DC P4600/P4610, PCIe HHHL

4 x 4 TB Intel SSD DC P4600/P4610, PCIe HHHL

Capacity Storage

Capacity of 10 TB (minimum)

Capacity of 10 TB (minimum)

Host Adapters

 

1 x 100HFA016LS Intel Omni-Path Host Fabric Interface Adapter, PCIe x16

Data Network Adapter

 

Intel® Ethernet Connection X722 with Intel® Ethernet Converged Network Connection X527-DA2/DA4
or
10 gigabit (Gb) Intel® Ethernet Converged Network Adapter X710

Host Network Adapter

 

Integrated 1 gigabit Ethernet (GbE)

Network Infrastructure

 

 

Data Network

 

1 x 100 Gb per second (Gbps) Intel Omni-Path 24x port switch

Management Network

 

1 x 1 Gbps 24x port switch

Intel® Omni-Path Architecture (Intel® OPA)

 

1 x Intel® Omni-Path Edge Switch (Intel® OP Edge Switch) 100 Series or better

Lustre* Storage Infrastructure**

 

 

Lustre MDS*

 

1 x metadata server

Platform

 

1 x Intel Server Board S2600WFT**

Processor

 

Intel Xeon Gold 6152 processor (12 cores, 3.0 GHz), Intel Xeon Gold 6226 processor (12 cores, 2.80 GHz), or a higher number Intel Xeon Scalable processor

Memory

 

192 GB or higher (12 x 16 GB DDR4-2666)

Disks

 

2 x 480 GB Intel SSD DC S3520 (mirrored operating system)

Host Adapters

 

1 x 12 Gbps Intel® RAID Controller RS3SC008, JBOD mode;

1 x 100HFA016LS Intel Omni-Path Host Fabric Interface Adapter, PCIe x16

Lustre OSS

 

2 x object storage server

Platform

 

1 x Intel Server Board S2600WFT**

Processor

 

Intel Xeon Gold 6136 processor (12 cores, 3.0 GHz), Intel Xeon Gold 6226 processor (12 cores, 2.80 GHz), or a higher number Intel Xeon Scalable processor

Memory

 

192 GB or higher (12 x 16 GB DDR4-2666)

Disks

 

2 x 480 GB Intel SSD DC S3520 (mirrored OS)

Host Adapters

 

1 x 12 Gbps Intel RAID Controller RS3SC008, JBOD mode;

1 x 100HFA016LS Intel Omni-Path Host Fabric Interface Adapter, PCIe x16

 Lustre OST

 

Object storage target

JBOD

 

1 x JBOD drive enclosure

Drives

 

Capacity 6–10 TB

Lustre MDT

 

Metadata target

JBOD

 

Intel® Storage System JBOD2224S2DP, 2U, dual-port**

Sas Ssds

 

4 x HGST SAS 400 GB*

Software

GATK*, BWA, and GATK workflows optimized for Intel® technologies

Optimized Cromwell workflow

Intel® GKL with optimized routines for accelerating developer codes

GenomicsDB*, specializing in large-scale variant analysis

HTCondor* or Slurm* job scheduler for running clustered analytics jobs

Docker* for running multiple jobs in isolated containers across a cluster

Apache Spark* for big data analytics processing

Lustre, the open source parallel file system, for high-performance storage

GATK, BWA, and GATK workflows optimized for Intel technologies

Optimized Cromwell workflow

Intel GKL with optimized routines for accelerating developer codes

GenomicsDB, specializing in large-scale variant analysis

HTCondor or Slurm job scheduler for running clustered analytics jobs

Docker for running multiple jobs in isolated containers across a cluster

Apache Spark for big data analytics processing

Lustre, the open source parallel file system, for high-performance storage

Firmware And Software Optimizations**

Intel® Advanced Vector Extensions 512 (Intel® AVX-512)

Linux* frequency governor—performance mode

Intel® Hyper-Threading Technology (Intel® HT Technology)—disabled

CPU power and performance policy—balanced performance

Workload configuration—balanced

Package C-state—C6(Retention) state

Processor C6—enabled

Hardware P-states—native mode

Hardware PM interrupt—disabled

Enhanced Intel SpeedStep® technology—enabled

Intel® Turbo Boost Technology—enabled

Energy-efficient turbo—enabled

Intel AVX-512

Linux frequency governor—performance mode

Intel HT Technology—disabled

CPU power and performance policy—balanced performance

Workload configuration—balanced

Package C-state—C6(Retention) state

Processor C6—enabled

Hardware P-states—native mode

Hardware PM interrupt—disabled

Enhanced Intel SpeedStep technology—enabled

Intel Turbo Boost Technology—enabled

Energy-efficient turbo—enabled